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Esperion Therapeutics Inc是一家制药公司。该公司专注于开发和商业化口服、每日一次的非他汀类药物,用于治疗与低密度脂蛋白胆固醇(LDL-C)升高作斗争的患者。该公司的苯乙双胍和苯乙双胍、依折麦布复合片是口服的、每日一次的非他汀类降LDL-C药物,适用于动脉硬化性心血管疾病(ASCVD)或杂合子家族性高胆固醇血症(HeFH)患者。该公司的产品包括NEXLETOL、NEXLIZET、NILEMDO和NUSTENDI。其NEXLETOL是一种ATP柠檬酸酯酶(ACL)抑制剂,通过减少胆固醇的生物合成和上调LDL受体来降低LDL-C。它的NEXLIZET和NUSTENDI含有硫辛酸和依折麦布,通过抑制胆固醇在肝脏的合成和在肠道的吸收,以互补的作用机制降低升高的LDL-C。
名称 | 年龄 | 任期 | 标题 |
---|---|---|---|
Daniel S. Janney | 56 | 2012 | Independent Director |
Nicole Vitullo | 65 | 2008 | Lead Independent Director |
Antonio M. Gotto | 87 | 2014 | Independent Director |
Sheldon L. Koenig | 56 | 2020 | President, CEO & Director |
Seth H. Z. Fischer | 66 | 2021 | Independent Director |
Alan Fuhrman | 65 | 2020 | Independent Non-Employee Director |
J. Martin Carroll | 74 | 2022 | Independent Chairperson |
Stephen Charles Rocamboli | 51 | 2022 | Independent Director |
Karin Bornfeldt | - | 2022 | Member of Scientific Advisory Board |
Tracy M. Woody | 53 | 2019 | Independent Director |
Jay P. Shepard | 65 | 2018 | Independent Director |
Erin A. Bohula | - | 2022 | Member of Scientific Advisory Board |
Gerald I. Shulman | - | 2022 | Member of Scientific Advisory Board |
R. Preston Mason | - | 2022 | Member of Scientific Advisory Board |
Dennis Bruemmer | - | 2022 | Member of Scientific Advisory Board |
Marilyn Glassberg | - | 2022 | Member of Scientific Advisory Board |
Peter Libby | 76 | 2022 | Member of Scientific Advisory Board |
Pradeep Natarajan | - | 2022 | Member of Scientific Advisory Board |
David E. Cohen | - | 2022 | Member of Scientific Advisory Board |
Jeffrey Bender | - | 2022 | Member of Scientific Advisory Board |
Gabrielle Fredman | - | 2022 | Member of Scientific Advisory Board |
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