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Arcturus Therapeutics Holdings Inc是一家晚期全球临床信使核糖核酸(mRNA)药物公司。该公司专注于传染病疫苗的开发以及肝脏和呼吸道罕见疾病领域的重大机遇。除了其mRNA平台,该公司的脂质纳米粒(LNP)输送系统LUNAR还有潜力实现多种核酸药物,其自扩增mRNA技术(自转录和复制RNA(STARR)技术)有潜力在较低剂量水平下提供更持久的RNA和持续的蛋白质表达。该公司使用STARR技术开发的产品有ARCT-021、ARCT-154和ARCT-165。其COVID-19候选疫苗ARCT-021基于其STARR技术平台,正在进行II期临床试验。其LUNAR-FLU疫苗由Liver Franchise ARCT-810 (LUNAR-OTC)和Lung Franchise ARCT-032 (LUNAR-CF)组成。
名称 | 年龄 | 任期 | 标题 |
---|---|---|---|
Andrew H. Sassine | 57 | 2018 | CFO & Director |
Peter C. Farrell | 79 | 2018 | Independent Chairman of the Board |
Karah Herdman Parschauer | 43 | 2019 | Director |
Joseph E. Payne | 49 | 2013 | Founder, President, CEO & Director |
Peter A. Patriarca | - | 2020 | Member of the Vaccine Platform Scientific Advisory Board |
Robert T. Schooley | - | 2020 | Member of the Vaccine Platform Scientific Advisory Board |
Eng Eong Ooi | - | 2020 | Member of the Vaccine Platform Scientific Advisory Board |
Jeffrey William Colyer | - | 2020 | Member of the Vaccine Platform Scientific Advisory Board |
Frederick G. Hayden | - | 2020 | Member of the Vaccine Platform Scientific Advisory Board |
Jonathan F. Smith | - | 2020 | Member of the Vaccine Platform Scientific Advisory Board |
Jing L. Marantz | 57 | 2021 | Independent Director |
John H. Markels | 56 | 2022 | Director |
Magda Marquet | 64 | 2018 | Independent Director |
Michael R. Hodges | - | 2014 | Member of Scientific Advisory Board |
Drew Weissman | - | 2015 | Member of Scientific Advisory Board |
James F. Barlow | 64 | 2018 | Independent Director |
Steven George Hughes | 55 | 2022 | Strategic Clinical Advisor & Member of Scientific Advisory Board |
Edward W. Holmes | 82 | 2019 | Independent Director |
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